Laser speckle imaging has become a widely used tool for dynamic imaging of blood flow, both in animal models and in the clinic. Speckles are produced when coherent light scattered back from biological tissue is diffracted through the limiting aperture of focusing optics.
With the advantages of the unique non-contact, high time and spatial resolution, rapid imaging, the laser speckle imager provides a new recording way for the life sciences basic research and clinical medical, which can achieve real-time dynamic blood flow monitoring and video imaging, it is the vital basis for understanding the organization, organ pathology and physiological indicators.
The technology does not need any contrast agent, the time resolution can be in milliseconds, the spatial resolution can be in microns. It also achieves the requirements of real-time observation of microvascular blood flow distribution and relative changes in values.